Peroxisomes are the cell structures that break down fatty
acids, oils and break down toxic substances. But peroxisome is also not a good
candidate for the Chief because there are many defects that come with this
organelle. One of the main defects that are widely known is the Zellwegger
syndrome. This disease is cause of defects in one of the 13 genes of the PEX
genes. This Zellwegger spectrum can have overlapping symptoms. The Zellewegger
syndrome results from “dysfunctional lipid metabolism and defects of bile acids
and plasmalogens”. There are many symptoms that can occur from this syndrome
and some of them affect the facial structures because it can make a high
forehead, neurological abnormalities, and even to the point of not being able
to move. The pain is very unbearable and the citizens deserve a better organelle as Chief. So once again we can see that peroxisome is not a good fit to run the
office as Chief Organelle.
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